Barely Significant
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Can Levothyroxine Be Taken as Evening Dose? Comparative Evaluation of Morning versus Evening Dose of Levothyroxine in Treatment of Hypothyroidism.

J Thyroid Res · 2011 · PMC3139142 · PMID 21785690

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hedged sentence
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The sentences

highly significantP value <.0001actually significant
Improvement in thyroid profile (increase in fT3 and fT4 and decrease in TSH) at 6 weeks and 12 weeks was seen both in the morning group as well as in the evening, and it was highly significant in comparison with their baseline thyroid function ( P value <.0001).

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