Barely Significant
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STAT3 activation in skeletal muscle links muscle wasting and the acute phase response in cancer cachexia.

PLoS One · 2011 · PMC3140523 · PMID 21799891

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hedged sentence
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closest p · 0.0× alpha
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The sentences

highly significantp = 1.0 e-323actually significant
Similarity of gene expression between the two groups was highly significant ( p = 1.0 e-323).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.