Barely Significant
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Histone H2B ubiquitylation and H3 lysine 4 methylation prevent ectopic silencing of euchromatic loci important for the cellular response to heat.

Mol Biol Cell · 2011 · PMC3145549 · PMID 21680712

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highly significantno p-value reported
This analysis ( Table 2 ) revealed highly significant enrichment of category 4 genes in 10 GO terms, three of which were directly relevant to the temperature-sensitive phenotype under consideration: 1) response to temperature stimulus, 2) response to heat, and 3) cellular response to heat.

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