Barely Significant
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LGI2 truncation causes a remitting focal epilepsy in dogs.

PLoS Genet · 2011 · PMC3145619 · PMID 21829378

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hedged sentence
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closest p · 0.0× alpha
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boldest claim

The sentences

highly significantp = 1.05×10 −23actually significant
Summarizing the results to this point, the genome-wide association study revealed a highly significant association in the vicinity of Lgi2 , an extremely strong association (p = 1.05×10 −23 ) with the protein-truncating c.1552A>T (p.K518X) sequence change in the gene, and no significant association with any other locus.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.