Barely Significant
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LGR5 is a negative regulator of tumourigenicity, antagonizes Wnt signalling and regulates cell adhesion in colorectal cancer cell lines.

PLoS One · 2011 · PMC3145754 · PMID 21829496

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The sentences

highly significantp<0.0001actually significant
The difference in tumour size between the LGR5 knockdown and the parental cells was highly significant (p<0.0001) at all time points, however the growth of tumours overexpressing LGR5 differed significantly from parental cells only for the first 10 days of the xenografts experiment ( Fig. 5A ).

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