Nicotinamide phosphoribosyltransferase/visfatin does not catalyze nicotinamide mononucleotide formation in blood plasma.

PLoS One · 2011 · PMC3149623 · PMID 21826208

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may be significantno p-value reported

Thus, it is likely that the synthesis of NAD is tightly regulated at the first steps of the pathway by the cellular concentration of ATP, and that based on the millimolar levels of normal cellular ATP this regulation may be significant during substantial depletion of ATP pools, such as that during cellular stress.

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