Stability of yellow fever virus under recombinatory pressure as compared with chikungunya virus.

Thus the levels of co-infection described here, specifically with regard to arthropod cells (electroporation of C 7 10 with 17D 5′ ΔE-Cherry and 17D 3′ ΔE-GFP RNAs reproducibly resulted in ≥10 5 co-infections), are highly significant because they suggest that even if every cell within the mosquito gut were simultaneously co-infected with two distinct flaviviruses, a recombinant virus would still not likely be produced.

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