Trans-eQTLs reveal that independent genetic variants associated with a complex phenotype converge on intermediate genes, with a major role for the HLA.

PLoS Genet · 2011 · PMC3150446 · PMID 21829388

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highly significantno p-value reported

Due to this highly significant enrichment of converging pairs of SNPs and its low estimated false-positive rate, we also ran an analysis where we had relaxed the FDR for trans -eQTLs to 0.50 ( Table S7 ).

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