Cdt1 proteolysis is promoted by dual PIP degrons and is modulated by PCNA ubiquitylation.

Nucleic Acids Res · 2011 · PMC3152358 · PMID 21493688

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may be significantno p-value reported

Our work confirms the importance of the downstream sequence, but shows that a positively charged region instead of a single residue is required for efficient Cdt1 proteolysis and thus there may be significant variation in the structure of CRL4 Cdt2 degrons.

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