Combined mRNA expression levels of members of the urokinase plasminogen activator (uPA) system correlate with disease-associated survival of soft-tissue sarcoma patients.

BMC Cancer · 2011 · PMC3152967 · PMID 21702998

Europe PMC DOI

hedged sentences

0.0540

closest p · 1.1× alpha

0.0540

boldest claim

The sentences

a trend towards significanceP = 0.054so close (0.05 < p ≤ 0.1)

We found an association between high PAI-1 and uPAR-del4/5 mRNA expression levels and an increased risk of tumor-related death for R0 patients using multivariate Cox regression analysis with relative risks (RR) of 6.55 (95%CI = 1.0-44.5) and 6.00 (95%CI = 0.8-47.1), respectively, with a trend towards significance ( P = 0.054 and P = 0.088, respectively; Table 3 ).

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highly significantno p-value reported

We recently reported a highly significant correlation between high antigen levels of uPA, PAI-1 or uPAR in tumor tissue, and of soluble uPAR in serum, with poor outcome of STS patients [ 20 ].

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.