A borderline significant QTL was identified on chromosome 11 (D11Mit38) for Ct.Ar/BW measured at 16 weeks.
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Genetically determined phenotype covariation networks control bone strength.
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Suggestive (37th percentile), significant (95th percentile), and highly significant (99.9th percentile) LRS scores were determined on a genome-wide basis by permutation testing (1000 times).( 41 ) Because several RI strains (AXB18, AXB19, and AXB20) were not considered independent owing to greater than 86% similarity in strain distribution patterns,( 42 ) marker regression analyses were run with AXB18 removed to confirm the significance levels of the QTLs.