highly significantP <10 −15
marginally significantP =0.01
Interestingly, we found a highly significant overlap between genes repressed in daGAL4 > UAS-dInR DN and those activated upon removal of dfoxo in that genetic context ( P <10 −15 ), while the overlap between genes activated in daGAL4 > UAS-dInR DN and repressed upon dfoxo deletion was marginally significant ( P =0.01).