A peptide mimetic targeting trans-homophilic NCAM binding sites promotes spatial learning and neural plasticity in the hippocampus.

PLoS One · 2011 · PMC3160849 · PMID 21887252

Europe PMC DOI

hedged sentences

0.0600

closest p · 1.2× alpha

0.0650

boldest claim

The sentences

a trend toward significancep = 0.06so close (0.05 < p ≤ 0.1)

There was a trend toward significance for GluA3 (t = 2.00, df = 16, p = 0.06), and levels from plannexin-treated rats were lower than controls following the probe test ( Figure 7C ).

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a trend towards significancep = 0.065so close (0.05 < p ≤ 0.1)

Further 2×2 ANOVAs performed on synapse density from the other spines categories failed to show an effect of plannexin or water maze training or their interaction [but note that a trend towards significance was found for plannexin treatment to reduce thin synapses (F 1,12 = 4.57, p = 0.065)].

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