Update on the management of diabetic polyneuropathies.

Diabetes Metab Syndr Obes · 2011 · PMC3160854 · PMID 21887102

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hedged sentence

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borderline significantno p-value reported

A borderline significant reduction in pain intensity has been demonstrated. 140 Topical clonidine (0.1% gel) has been evaluated in a Phase II, double-blind RCT in 166 subjects with DPN.

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