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Inverse association between methylation of human papillomavirus type 16 DNA and risk of cervical intraepithelial neoplasia grades 2 or 3.

PLoS One · 2011 · PMC3161083 · PMID 21887341

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The inverse association remained statistically significant or marginally statistically significant when the methylation status was based on CpGs in the enhancer and promoter, separately.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.