Barely Significant
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Ketamine influences CLOCK:BMAL1 function leading to altered circadian gene expression.

PLoS One · 2011 · PMC3161090 · PMID 21887357

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a possible trendno p-value reported
Low doses of ketamine are instead associated with a sharper rise in Cry1 levels at CT 24, suggesting a possible trend toward phase delay.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.