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An evaluation of ciprofloxacin pharmacokinetics in critically ill patients undergoing continuous veno-venous haemodiafiltration.

BMC Clin Pharmacol · 2011 · PMC3161942 · PMID 21816053

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possibly significantno p-value reported
In healthy volunteers, the hepatic route accounts for approximately 20% of elimination, with transintestinal excretion also playing a possibly significant role.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.