This was also confirmed in a recent meta-analysis, which reported the incidence of overall hypoglycaemia to be increased when glinides were added to a maximum tolerated dose of metformin (RR 7.92 (95%CI 1.45-43.21), while the risk with sulfonylureas was also elevated but this was not significantly significant (RR 2.63; 95%CI 0.76-9.13) [ 4 ].
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Antidiabetic pharmacotherapy and anamnestic hypoglycemia in a large cohort of type 2 diabetic patients--an analysis of the DiaRegis registry.
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