Sprouty 2 is an independent prognostic factor in breast cancer and may be useful in stratifying patients for trastuzumab therapy.

PLoS One · 2011 · PMC3166119 · PMID 21909357

Europe PMC DOI

hedged sentence

0.0900

closest p · 1.8× alpha

0.0900

boldest claim

The sentences

near significancep = 0.09so close (0.05 < p ≤ 0.1)

The cut-point for Spry2 expression were calculated as described in the Materials and Methods , such that as well as showing high significance for difference in survival (p = 0.0069; Figure 5B ), the cutpoint for Spry2 expression also maintained near significance with Monte Carlo simulations (p = 0.09) and correction for type I error (Miller-Seigmund p value = 0.12).

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