Moderate weight reduction in an outpatient obesity intervention program significantly reduces insulin resistance and risk factors for cardiovascular disease in severely obese adolescents.

Int J Endocrinol · 2011 · PMC3166723 · PMID 21904547

Europe PMC DOI

hedged sentence

0.0001

closest p · 0.0× alpha

0.0001

boldest claim

The sentences

highly significantP > 0.0001actually significant

We noted a highly significant correlation between leptin levels and HOMA ( r = 0.433, P > 0.0001) as well as between leptin levels and peak insulin levels ( r = 0.61, P < 0.006) before treatment.

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