Permutation criteria to evaluate multiple clinical endpoints in a proof-of-concept study: lessons from Pre-RELAX-AHF.

Clin Res Cardiol · 2011 · PMC3167045 · PMID 21416190

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a positive trendno p-value reported

Results for 3 of these 36 comparisons (one permuted dose group compared against placebo for 3 of the 9 endpoints), and the number of endpoint comparisons out of 9 with a positive trend for that dose group, are shown for the 10 illustrative permutation samples in Table 3 .

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