Metabolic responses to high-fat diets rich in n-3 or n-6 long-chain polyunsaturated fatty acids in mice selected for either high body weight or leanness explain different health outcomes.

In contrast, feeding a HFD to DUhTP mice did not result in significant changes in fat deposition with abdominal adipose tissue weight reaching a small trend towards increased levels (p = 0.06) in the n-3 HFD-fed animals compared to the standard chow-fed group (Table 2 ).

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