Barely Significant
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Unique Properties of Hepatocarcinogenesis-Resistant DRH Rat Hepatocytes Linked or Not Linked to the Drh1 Locus on Rat Chromosome 1.

Int J Hepatol · 2011 · PMC3170802 · PMID 21994856

Europe PMCDOI
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highly significantno p-value reported
Genetic analysis has demonstrated that resistance is a dominant trait in a cross of DRH and Donryu rats [ 4 ] and that the number and size of preneoplastic hepatocytic lesions and the expression levels of glutathione-S-transferase-placental form (GST-P) mRNA and protein, a marker for preneoplastic hepatocytes, are strongly affected by highly significant quantitative trait loci (QTL) on rat chromosomes 1q ( Drh1 ) and 4q ( Drh2 ) [ 5 , 6 ].

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