A galU mutant of Francisella tularensis is attenuated for virulence in a murine pulmonary model of tularemia.

BMC Microbiol · 2011 · PMC3173336 · PMID 21819572

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highly significantno p-value reported

Conclusions Disruption of the galU gene of FTLVS has little if any effect on its infectivity, replication, or dissemination in vitro , but it resulted in highly significant virulence attenuation.

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