Barely Significant
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Replication protein A (RPA) hampers the processive action of APOBEC3G cytosine deaminase on single-stranded DNA.

PLoS One · 2011 · PMC3174200 · PMID 21935481

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The sentences

highly significantP<10 −6actually significant
Despite the fact that single, silent substitutions can not be detected in the selective system, we observed a highly significant correlation in mutable positions between the in vivo and in vitro spectra (Pearson linear correlation coefficient = 0.79, P<10 −6 ).

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