Case-control study for colorectal cancer genetic susceptibility in EPICOLON: previously identified variants and mucins.

BMC Cancer · 2011 · PMC3176240 · PMID 21819567

Europe PMC DOI

hedged sentences

0.0900

closest p · 1.8× alpha

0.0900

boldest claim

The sentences

borderline significanceP -value = 0.09so close (0.05 < p ≤ 0.1)

The rs3803185 variant was not significantly associated with CRC risk in an external cohort (MCC-Spain), but it still showed some borderline significance in the pooled analysis of both cohorts (OR = 1.08, 95% CI = 0.98-1.18, P -value = 0.09, log-additive 0, 1, 2 alleles).

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borderline significantno p-value reported

In the joint analysis for both stages, results were only significant for rs3803185 (OR = 1.12, 95% CI = 1.00-1.25, P -value = 0.04, log-additive 0, 1, 2 alleles) and borderline significant for rs698 and rs2102302.

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