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Epidermal growth factor receptor plays an anabolic role in bone metabolism in vivo.

J Bone Miner Res · 2011 · PMC3179301 · PMID 21542005

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a decreasing trendno p-value reported
Effects of the inhibitors also were apparent in the femoral cortical compartment ( Table 2 ), where cortical BMD, cortical area and thickness, and periosteal and endosteal perimeters exhibited a decreasing trend in inhibitor-treated mice.

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