Barely Significant
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Prevention: an achievable goal in personalized medicine.

Dialogues Clin Neurosci · 2009 · PMC3181930 · PMID 20135902

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highly significantno p-value reported
52 , 53 If a high-risk group has a relative risk of developing a depressive disorder of 4.00, this will be highly significant (if the research population is large enough).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.