Barely Significant
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Whole genome association studies in complex diseases: where do we stand?

Dialogues Clin Neurosci · 2010 · PMC3181943 · PMID 20373665

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borderline significanceno p-value reported
highly significantno p-value reported
60 The associations with MEIS1 and BTBD9 were quickly replicated in two subsequent studies, 61 , 62 but the MAP2K5/LBXCOR1 appears to be weaker, showing a borderline significance in one study only 62 Although the risk associated with MEIS1 and BTBD9 (ranging from 1.5 to 3.7 59 , 60 , 62 , 63 ,606263) is substantially lower than those described above, they do appear to be real and highly significant risk factors for RLS.

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