Hematological changes as prognostic indicators of survival: similarities between Gottingen minipigs, humans, and other large animal models.

Here, we measured the ratio between CRP and platelet counts (vii); a highly significant negative association with survival was found starting at day 10 (r s = −.65, p≤0.001), more so than CRP values alone; a statistically significant difference between 14 day CRP levels in surviving versus non-surviving animals was confirmed in the current study (p<0.05).

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