Mucin variable number tandem repeat polymorphisms and severity of cystic fibrosis lung disease: significant association with MUC5AC.

PLoS One · 2011 · PMC3188583 · PMID 21998660

Europe PMC DOI

hedged sentences

0.0790

closest p · 1.6× alpha

0.0790

boldest claim

The sentences

a trend toward significancep = 0.079so close (0.05 < p ≤ 0.1)

There was a trend toward significance for MUC1 (p = 0.079; Figure 2A ) but not for MUC2 (p = 0.143; Figure 2B ) or MUC 7 (p = 0.284; Figure 2D ).

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highly significantno p-value reported

Likelihood ratio testing of the VNTR three-allele system versus the two-allele system showed highly significant evidence of improved fits from the three-allele system ( Figure 4 ), indicating that LD structure with nearby SNPs was better explained by considering the 6.3 and 6.4 kb alleles as separate alleles, rather than as the same allele (as in Figure 3 , where both alleles are grouped as “short”).

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