Long term risk for hypertension, renal impairment, and cardiovascular disease after gastroenteritis from drinking water contaminated with Escherichia coli O157:H7: a prospective cohort study.

In contrast, when we increased the specificity of the outcome to include the presence of both structural and functional renal impairment, the hazard ratio increased from 1.15 to 3.41 and was highly significant despite a dramatic reduction in the event rate (from 572 to 30).

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