This is highly significant, as, overall, only 875 genes (8.1%) were downregulated 1.5 fold in RBKO background, 827 genes (7.7%) were downregulated 1.5 fold in TKO villi, and 820 genes (7.6%) were downregulated 1.5 fold in QKO .
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The retinoblastoma tumor suppressor regulates a xenobiotic detoxification pathway.
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