Asymptomatic SIV-infected macaques also showed a similar tendency to higher APOBEC3 mRNA levels compared with uninfected animals, which however failed to reach significance after post hoc correction for multiple comparisons (Figure 1G-J ).
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Increased APOBEC3G and APOBEC3F expression is associated with low viral load and prolonged survival in simian immunodeficiency virus infected rhesus monkeys.
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