Spearman rank correlations between overall average RNFL thickness and visual function scores were highly significant yet modest in magnitude, suggesting that visual dysfunction may occur in some patients in the absence of (or perhaps in advance of) RNFL axonal loss (Spearman r [ r s] = 0.33 and P < .0001 for low-contrast letter acuity, r s = 0.31 and P < .0001 for contrast sensitivity, r s = 0.26 and P = .0005 for high-contrast VA) [ 10 ].
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Optical coherence tomography in multiple sclerosis and neuromyelitis optica: an update.
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