Recent advances in the pathogenesis and management of cast nephropathy (myeloma kidney).

Bone Marrow Res · 2011 · PMC3199932 · PMID 22046563

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highly significantno p-value reported

Renal failure is highly significant in myeloma, as patient survival can be stratified by the severity of the renal impairment.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.