Notably, in the animals treated with the control rAd EV, there was an interesting trend that developed with the 6 h post-infection group having the greatest ALT levels and viral titers, followed by the 24, 48, and −24 h groups.
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Use of recombinant adenovirus vectored consensus IFN-α to avert severe arenavirus infection.
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The sentences
When DEF201 was administered 6 or 24 h after challenge, highly significant protection was observed ( Figure 5 ).