Hypervirulent K. pneumoniae secretes more and more active iron-acquisition molecules than "classical" K. pneumoniae thereby enhancing its virulence.

The metastatic spread of hvKP1 from the subcutaneous compartment to the blood, eye, kidney, spleen, liver and lungs was greater when hvKP1 was grown in the presence of conditioned ascites, compared to unconditioned ascites at all times post-bacterial challenge (24 and 48 hours) and this difference was statistically significant or demonstrated a trend towards significance for most comparisons ( Figure 5 ).

also in 2,760 other papers