The impact of local and regional recurrence on distant metastasis and survival in patients treated with breast conservation therapy.

J Breast Cancer · 2011 · PMC3200514 · PMID 22031800

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marginal significanceno p-value reported

In multivariate analysis, younger age (≤35 years) (hazard ratio [HR], 1.79; 95% confidence interval [CI], 1.01-3.15; p =0.043), positive lymph node (HR, 2.34; 95% CI, 1.47-3.71; p <0.001), early LR (HR, 4.76; 95% CI, 1.69-13.34; p =0.003), and early RR (HR, 18.16; 95% CI, 6.34-52.00; p <0.001) were significantly related with lower DRFS, whereas tumor size (HR, 1.58; 95% CI, 1.00-2.51; p =0.05) had marginal significance.

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