Impact of Plasma-Lyte pH 7.4 on acid-base status and hemodynamics in a model of controlled hemorrhagic shock.

29 In addition, the induction or maintenance of hyperlactemia by LR solution (as suggested by our results) may be significant when larger volumes are infused.

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The infusion of normal saline induced a negative SBE and a highly significant increase in the plasma chloride concentration, whereas the infusion of Ringer's lactate and Plasma-Lyte pH 7.4 induced a positive SBE and a negative plasma chloride concentration ( Figure 1 ).

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