Is there a genetic cause for cancer cachexia? - a clinical validation study in 1797 patients.

Br J Cancer · 2011 · PMC3208484 · PMID 21934689

Europe PMC DOI

hedged sentences

0.0199

closest p · 0.4× alpha

0.0199

boldest claim

The sentences

a trend toward significanceP =0.0199actually significant

The acylpeptide hydrolase ( APEH ) SNP rs 4855881 showed a trend toward significance ( P =0.0199), but the P -value was still above the B–H criterion of 0.011 that we pre-specified as denoting significance.

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a trend towards significanceno p-value reported

Conclusion: This study failed to detect any significant association between any of the SNPs analysed and cachexia; although two SNPs from the APEH gene had a trend towards significance.

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