A highly significant loss of GSTPi expression was detected in breast cancer cells, both at the primary and metastatic sites, as compared with benign breast epithelial cells (Fisher's exact test P <0.001, Table 2 ).
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GSTPi-positive tumour microenvironment-associated fibroblasts are significantly associated with GSTPi-negative cancer cells in paired cases of primary invasive breast cancer and axillary lymph node metastases.
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