Comparative Molecular Field Analysis (CoMFA) and Comparative Molecular Similarity Indices Analysis (CoMSIA) studies on α(1A)-adrenergic receptor antagonists based on pharmacophore molecular alignment.

Int J Mol Sci · 2011 · PMC3211024 · PMID 22072933

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highly significantno p-value reported

This yielded a highly significant q 2 value of 0.840 (with S cv = 0.476, using four components), which indicates that it is a model with high statistical significance; a q 2 value of 0.6 is considered statistically significant in CoMFA and CoMSIA studies [ 39 ].

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