Influence of chylomicron remnants on human monocyte activation in vitro.

Quantification of the staining density using digital image analysis showed that there was a highly significant increase in the lipid content of CRLP-treated monocytes when compared to cells exposed to the control preparation ( P < 0.001, paired Student's t test) ( Figure 1 B).

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This is likely to be significant for development of atherosclerosis, particularly when the removal of CMR from the blood is delayed as occurs in relatively common conditions such as obesity and type 2 diabetes [28] .

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