Antibiotic-refractory Lyme arthritis is associated with HLA-DR molecules that bind a Borrelia burgdorferi peptide.

J Exp Med · 2006 · PMC3212725 · PMID 16585267

Europe PMC DOI

hedged sentences

0.0060

closest p · 0.1× alpha

0.0500

boldest claim

The sentences

highly significantP = 0.006actually significant

Moreover, when the DRB1 and DQA1-DQB1 alleles were analyzed separately, the frequencies of the DRB1 alleles showed a highly significant difference (log likelihood test, P = 0.006; exact test, P = 0.008) with a large effect size (Wn = 0.38; Table II ).

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of borderline significanceP = 0.05actually significant

When these haplotypes were compared between Lyme arthritis patients and the control population, a difference of borderline significance was found (log likelihood test, P = 0.05), but the effect size statistic was low (Wn = 0.13), suggesting that the two groups had only minimal overall differences in HLA types.

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