highly significantp ≤ 0.0001
Its frequency was significantly higher in Rufiji than in Kilombero-Ulanga between 2001 and 2002, yet the increase of this allele during 2001- 2002 period was highly significant in both Kilombero-Ulanga (p ≤ 0.0001) and Rufiji (p ≤ 0.0001).