highly significantP < 0.05
P < 0.001 was considered as highly significant, P < 0.05 or P < 0.01 as significant, and P < 0.10 or P > 0.01 as insignificant.
P < 0.001 was considered as highly significant, P < 0.05 or P < 0.01 as significant, and P < 0.10 or P > 0.01 as insignificant.