Integrated genomic approaches to identification of candidate genes underlying metabolic and cardiovascular phenotypes in the spontaneously hypertensive rat.

Physiol Genomics · 2011 · PMC3217321 · PMID 21846806

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highly significantno p-value reported

Quantitative trait transcript (QTT) analysis in the RI strains showed highly significant correlation between cis -eQTL transcript abundance and clinically relevant traits such as systolic blood pressure and blood glucose, with the physical location of a subset of the cis -eQTLs colocalizing with “physiological” QTLs (pQTLs) for these same traits.

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