GISTIC2.0 facilitates sensitive and confident localization of the targets of focal somatic copy-number alteration in human cancers.

Genome Biol · 2011 · PMC3218867 · PMID 21527027

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highly significantno p-value reported

For example, in our GBM samples, gene-based scoring did not identify a region just outside of PCHD9 on chr13q21.3 that scored as highly significant (q-value = 4.4e-9) using the standard marker-based score (Supplementary Figure S4b in Additional file 7 ).

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