Co-immunization of plasmid DNA encoding IL-12 and IL-18 with Bacillus Calmette-Guérin vaccine against progressive tuberculosis.

Yonsei Med J · 2011 · PMC3220262 · PMID 22028167

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highly significantno p-value reported

In the present study, the BCG vaccine induced highly significant protective efficacy against TB in the early stage of infection, and the co-immunization of IL-12 DNA vaccine constructs with the BCG vaccine showed a little additive effect on the BCG vaccine in the spleens.

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